Kaena: The Prophecy (2003) on Netflix

AXIS, a gigantic coiling plant, stretches high above the clouds... At its center is a village whose people are in mortal danger because Axis is withering... it's sap is drying up. The people beg their gods for help... but to no avail. Compelled by a mysterious force, Kaena, a rebellious, high-spirited teenage girl will defy the High Priest and her people's ancestral beliefs to take the perilous journey through the Axis and discover what dark secrets lie beyond the clouds... A dying world, an evil force, a terrible secret...