Harley Davidson and the Marlboro Man (1991) on Netflix

The tough biker Harley and his no less tough cowboy friend Marlboro learn that an old friend of theirs will lose his bar, because a bank wants to build a new complex there and demands 2.5 million dollars for a new contract in advance. Harley and Marlboro decide to help him by robbing the corrupt bank. Unfortunately they rob the wrong safety transport and get hold of an amount of a new synthetic drug. Now they are targeted both by criminal bankers and killers of the drug mob.